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. 2011 Apr 13;286(23):20569–20581. doi: 10.1074/jbc.M111.220962

FIGURE 6.

FIGURE 6.

Deletion of Egr-1 function reduces phosphorylation of tau and PP1 in mouse brain. Fresh mouse brains of the indicated genotype (n = 3 per group) were homogenized, and each homogenate was subjected to Western blot analysis using the indicated antibodies. A, Western blots. B, relative amounts. Relative amounts were determined from the band intensities of the respective proteins in A as in Fig. 2. Values are the mean ± S.E. from three brain samples in each group and are expressed as the -fold of Egr-1+/+ control. *, p < 0.001; **, p < 0.05 with respect to Egr-1+/+ control (t test). pPP1, phosphorylated PP1.