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. 2011 Jan 13;8(5):296–299. doi: 10.1159/000323190

Table 2.

Selected SNPs in the CHRNA3-CHRNA5-CHRNB4 cluster in relation to PD1

SNPs Minor allele frequency
All participants
Never smokers
Ever smokers
of controls of cases OR (95% CI)2 P OR (95% CI)2 P OR (95% CI)2 P
rs8034191 0.33 0.34 1.08 (0.93–1.25) 0.3 1.18 (0.93–1.49) 0.2 1.01 (0.84–1.22) 0.9
rsl7486278 0.33 0.34 1.06 (0.92–1.23) 0.4 1.14 (0.90–1.43) 0.3 1.01 (0.83–1.22) 0.9
rs569207 0.24 0.25 1.05 (0.90–1.22) 0.6 0.91 (0.71–1.17) 0.5 1.18 (0.97–1.44) 0.1
rsl6969968 0.33 0.34 1.07 (0.92–1.23) 0.4 1.16 (0.92–1.46) 0.2 1.00 (0.83–1.21) 0.98
rs578776 0.29 0.29 1.00 (0.86–1.16) 0.96 0.85 (0.67–1.08) 0.2 1.12 (0.93–1.35) 0.3
rsl051730 0.32 0.34 1.07 (0.93–1.24) 0.3 1.16 (0.92–1.46) 0.2 1.02 (0.84–1.23) 0.9
rs6495308 0.24 0.25 1.03 (0.89–1.21) 0.7 0.89 (0.69–1.15) 0.4 1.17 (0.96–1.43) 0.1
1

The numbers of cases/controls for each analysis were: 788/911 for all participants, 363/318 for never smokers, 418/590 for ever smokers.

2

ORs (95% CI) for PD per risk allele under the additive model.

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