Table 1. Calculated potencies (depicted as mean with corresponding CI*) of IVIg, IVIg-SA (+), their Fab fragments and Fc protK digests to inhibit SNA lectin binding to IgG.
| IVIg | IVIg-SA(+) | IVIg-SA(−) | |
| IgG | 1 | 13 (12.0–14.8) | n.d. |
| Fab | 0.49 (0.44–0.54)a | 3.6 (3.2–4.2)a | n.d. |
| 7.0 (6.0–8.3)b | |||
| Fc protK digest | 0.39 (0.34–0.46)a | 0.39 (0.33–0.45)a | 0.41 (0.36–0.46)a |
| 0.87 (0.73–1.0)c | 0.95 (0.81–1.11)c |
a
) relative to IVIg-IgG.
b
) relative to IVIg-Fab.
c
) relative to IVIg-Fc protK digest.
*CI confidence interval.
n.d. not determined.