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. 2011 Jun 23;6(6):e21360. doi: 10.1371/journal.pone.0021360

Table 3. Local slopes from the age-specific kinetics of neuronal loop-DNA digestion.

Nucleoids
P0 P7 P80 P540
TIME (min) % of DNA attached to NM S % of DNA attached to NM S % of DNA attached to NM S % of DNA attached to NM S
05 100.055.9 −8.8 100.049.2 −10.2 100.066.4 −6.7 100.076.5 −4.7
515 55.924.5 −3.1 49.224.3 −2.5 66.437.7 −2.9 76.557.0 −2.0
1530 24.517.6 −2.2 24.320.5 −0.3 37.725.0 −0.8 57.046.1 −0.7
3060 17.68.8 −3.4 20.517.4 −0.1 25.017.4 −0.3 46.126.4 −0.7

Local slopes (S) between time points from the corresponding kinetics of loop-DNA digestion of neuronal nucleoids from different post-natal ages. Topological zones relative to the NM (Fig. 3) were established according to such local slopes. New-born (P0), 7-day-old (P7), adult (P80), old (P540) rats.