Table 5.

Loss of Anp32b does not reveal any defect attributable to Anp32e

	Anp32b+/+			Anp32b+/−			Anp32b−/−
	Anp32e+/+	Anp32e+/−	Anp32e−/−	Anp32e+/+	Anp32e+/−	Anp32e−/−	Anp32e+/+	Anp32e+/−	Anp32e−/−
Mendelian	6	11	6	11	22	11	6	11	6
Expected	8	16	8	12	25	12	2	3	2
Observed	9	13	10	14	21	15	3	2	1

Number of double-mutant mice arising from the intercrossing of Anp32e^+/−;Anp32b^+/− mice. “Mendelian” indicates the distribution for the indicated total number of mice under conditions of normal Mendelian segregation. “Expected” indicates the distribution for the Mendelian distributed numbers with integration of the observed rates of Anp32b lethality (Table 1). “Observed” indicates the actual numbers of mice of the noted genotypes obtained. No statistically significant deviation from “Expected” values was observed using χ² analysis.