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. 2011 Jun 6;108(25):10260–10265. doi: 10.1073/pnas.1106695108

Fig. 2.

Fig. 2.

Transepithelial electrophysiological properties in non-CF and CF epithelia. Gt (A), Isc (C), and Vt (E) under basal conditions and following the sequential additions indicated in legend of Fig. 1. Changes in Gt (ΔGt) (B), Isc (ΔIsc) (D) and Vt (ΔVt) (F) with treatments shown in A, C, and E. Data are mean ± SEM from 261 non-CF donors and 74 CF donors; data for each donor were the average of measurements from 1–12 epithelia (three epithelia were measured for most donors). In some cases error bars are hidden by symbols. *Difference from non-CF, P < 0.05, unpaired t test. (G and H) Data as in C and D but from excised epithelia (n = 10). Cl− current was inhibited using 100 μM GlyH-101 rather than bumetanide, so values after addition of an inhibitor are not directly comparable. Data from cultured non-CF epithelia (C and D) are shown for comparison.