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Effect of Cl−-free solution on the electrophysiological response to amiloride. Gt, Isc, and Vt under basal conditions and after amiloride addition in Cl−-containing (A–C) and Cl−-free (D–F) solutions. n = 12 non-CF and 13 CF epithelia for Cl−-containing solutions and 15 non-CF and 14 CF epithelia for Cl−-free solutions. *Difference in CF vs. non-CF epithelia, P < 0.05, unpaired t test.
