Fig. 7.

A. Axial T₂-weighted fast spin-echo image (TR (repetition time)/TE (echo time): 3100/135 milliseconds) at 3 T with combined body and spine matrix coils for localization of the enlarged lymph node (arrows). I, iliac bone; S, sigmoid; V, iliac vessels. B. The phase-corrected ¹H-MR spectrum (without baseline correction) obtained from the TE-averaged and combined water and lipid-suppressed single voxel MR spectroscopy measurement. A peak at 4.7 ppm for residual water spins and a peak at about 3.2 ppm assigned to the methyl groups of choline-containing compounds (tCho) were observed. Note the absence of lipid signals from 1 to 2.5 ppm. The coronal reference image from the T₁-weighted 3-dimensional gradient-echo sequence (TR/TE: 6.47/2.54 milliseconds) and the axial T₂-weighted fast spin-echo image are shown to indicate the voxel placement. C. An axial spectral map of all voxels inside the volume-of-interest from the ¹H-MR spectroscopic imaging measurement (TR/TE: 1500/100 milliseconds) in which the tCho resonances are underlined. Outside the lymph node, large lipid signals are present; the tCho signal is only present inside. D. Interpolated coronal and axial tCho color-coded maps constructed using the integral of a Gaussian fit to the tCho signal. Reprinted with permission from [101].