TGFβ1 expression in AD kidneys. Control kidneys show TGFβ1 staining in interstitium of renal papilla (A, arrow) and cortex (B, white arrow), and glomeruli (B, black arrow). Moderate mgb−/− kidneys show expanded TGFβ1 staining within medullary tubules (C, arrows), cortical and medullary interstitial cells (D,E, arrows), and glomeruli (F, arrow). Severe mgb−/− kidneys show expanded TGFβ1 staining in cortical tubules (G), glomeruli (G, GL), medulla (H), interstitial cells (H, arrows), and renal pelvis (RP) urothelium (I, arrows). 40X.