FIG. 5.
Inhibition of p38 increases HSC engraftment after secondary transplantation. Bone marrow MNCs were harvested from the primary recipients 20 weeks after transplantation. They (5×105) were transplanted into a lethally irradiated mouse along with 2×105 competitors. The donor cell engraftment in peripheral blood was determined 12 weeks after transplantation. The data are presented as mean±SE (n=7 mice/group) of percent of engraftment of total donor cells (A) and donor-derived myeloid cells (B), B cells (C) and T cells (D).