Table 3. Summary of the results obtained from the analysis of microglia and astroglial activation in the SNpc after MPTP treatment of wild type (C57BL6), IFNγ(−/−) and TNFα(−/−) mice.
| Microglia | Increase of F4/80+ cells | Increase in # of branches and tips | Increase of cell body size |
|---|---|---|---|
| C57BL6 | +++ | +++ | +++ |
| IFNγ(−/−) | − | ++ | − |
| TNFα(−/−) | + | +++ | ++ |
|
Astroglia |
Increase of GFAP+ cells |
Increase in # of branches and tips |
Increase of cell body size |
| C57BL6 | +++ | +++ | +++ |
| IFNγ(−/−) | − | +++ | +++ |
| TNFα(−/−) | − | − | − |