Table 4.
Result | Number (%) |
---|---|
Tumor resected | 42 (95%)(a) |
Primary only | 12 (27%) |
With lymph node metastases | 30 (68%) |
With liver metastases | 18 (41%) |
Type Primary surgery | |
Enucleation | 5 (12%) |
Resection | 36 (86%) |
Partial pancreatectomy | 23 (55%) |
Whipple resection | 10 (23%) |
Total pancreatectomy | 2 (5%) |
Liver resection | 19 (45%) |
Wedge resection | 10 (23%) |
Lobectomy | 9 (21%)(b) |
Vascular reconstruction | 9 (21%) |
SMV-portal vein | 9 (21%) |
SMA | 1 (2%) |
Surgical complications | |
Surgical death | 0 (0%) |
Complications | 12(28%)(c) |
Surgical result | |
Immediate tumor free | 18 (42%)(d) |
Recurrence | 5 (12%) (d) |
Time to recurrence years | |
Mean ± SEM | 1.7 ± 0.6 |
[range] | [0.5-3] |
Long term disease-free | 14 (33%)(d) |
Status Last follow-up | |
Alive | 34 (77%) |
Dead | 10 (23%) |
Years surgery to death | |
Mean ± SEM | 5.5 ± 0.3 |
[range] | [3-8] |
Duration of follow-up (yrs) | |
Time from surgery | |
Mean ± SEM | 5.7 ± 1.0 |
[range] | [1.3-21.2] |
Time from diagnosis | |
Mean ± SEM | 12.7 ± 1.2 |
[range] | [3.9-25.8] |
Other anti-tumor treatment | 18 (43%) |
Chemotherapy | 12 (28%) |
Other | 10 (23%)(e) |
Percentage based on 24 patients who underwent surgical exploration. Two patients had unresectable disease. See Table 3 footnote.
Include a trisegmentectomy (n=1), l hepatic lobe resection(n=4), and segmentectomy (n=4)
Complications include postoperative pancreatitis (n=1), abscess (n=4), wound infection (n=3), bile duct injury (n=1), leak at pancreaticojejunostomy (n=2) and ischemic bowel (n=1).
Disease free status and recurrence based on serial imaging studies as described in Methods
Patients treated with alpha-interferon (n=2), somatostatin analogues (n=9) or PRRT (n=1). Two that received alpha-interferon also got somatostatin analogues