Table 5.
Possible prognostic factors for prolonged disease-free survival postresection
| Variable present | Number (%) | Significance | |
|---|---|---|---|
| Disease-free last follow-up | |||
| Yes (n=20) | No (n=24) | ||
| General features | |||
| Male gender | 10/20 (50%) | 10/24 (41%)a | ns |
| Caucasian race | 19/20 (95%) | 19/24 (79%) | ns |
| NF-PET present | 9/20 (45%) | 7/24 (29%) | ns |
| MEN-1 present | 5/20 (25%) | 7/24 (29%) | ns |
| Hormone elevation >11.6 fold | 8/20 (40%) | 8/24 (33%) | ns |
| Pre-operative imaging | |||
| Primary>3.7 cm | 11/20 (55%) | 17/24 (71%) | ns |
| Primary: pancreatic head/duodenum | 13/20 (65%) | 17/24 (71%) | ns |
| Possible Portal vein involvement | 14/20 (70%) | 20/24(83%) | ns |
| Possible liver metastases present | 6/20 (30%) | 12/24 (50%) | ns |
| Surgical findings | |||
| Age surgery>47 yrs | 14/20 (70%) | 11/24 (46%) | ns |
| Primary tumor: pancreas | 14/20 (70%) | 16/24 (66%) | ns |
| Primary size>3 cm | 11/20 (55%) | 15/24 (63%) | ns |
| Lymph node metastases present | 14/20 (70%) | 19/24 (79%) | ns |
| Liver metastases found | 2/20 (10%) | 16/24 (66%) | <0.0001 |
| Invasion/encasement of vessel | 7/20 (35%) | 8/24 (33%) | ns |
| Surgical treatment/result | |||
| Liver resection | 3/20 (15%) | 16/24 (66%) | <0.001 |
| Vascular reconstruction | 5/20 (25%) | 4/24 (17%) | ns |
| Immediate postoperative = tumor free | 20/20 (100%) | 11/24 (46%) | 0.0001 |
| Surgical followup | |||
| Alive last follow-up | 20/20 100%) | 14/24 (58%) | <0.0001 |
| Last follow-up>7.5 yrs from surgery | 6/20 (30%) | 11/24 (45%) | ns |
| Other antitumor treatment postoperative | 0/20 (0%) | 16/24 (66%) | <0.0001 |
(a)
Proportions compared by Fisher's exact test.