TGM2 suppression reduced expression of c-FLIP-1L but not Mcl-1L and COX-2. A and B, the indicated cells were treated with cystamine (CTM; 1 mm) overnight or were left untreated. c-FLIP-1L, Mcl-1L, and COX-2 were detected by Western blot. β-Tubulin was detected as an input control. C, A549-TR cells were transfected with TGM 2 siRNA (pool) or NC siRNA. Forty-eight hours after transfection, cell lysates were prepared, and the indicated proteins were detected by Western blot. β-Tubulin was detected as an input control. Fold changes were calculated with the control taken as 1.