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Decreased serum IgA levels and impaired antibody responses to TNP-Ficoll in TACI+/− mice on the C57BL/6 background. A, TACI and B220 expression on splenocytes from TACI+/+, TACI+/−, and TACI−/− mice on the C57BL/6 background. B, Serum IgM, IgG, and IgA levels from nonimmunized 8- to 12-week-old mice. C, IgM and IgG anti-TNP antibody responses to TNP-Ficoll. The results in Fig 4, B and C, are presented and analyzed as in Fig 2 (n = 10-12 mice per group).
