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. 2009 Dec 21;37(4):839–849. doi: 10.1093/schbul/sbp151

Fig. 3.

Fig. 3.

Brain Regions with Significant Reduced Cortical Thickness in UHR Subjects Compared with HC Subjects. In the left hemisphere, the cortical thickness was decreased in superior temporal gyrus (L1), anterior cingulate cortex (ACC, L2), parahippocampal cortex (L3), and medial superior frontal cortex (L4). In the right hemisphere, the cortical thickness was reduced in dorsal ACC (R1), rostral ACC (R2), inferior frontal cortex (R3), and inferior parietal cortex (R4). All these regions showed statistically significant differences among 3 groups. In the boxplot, the x-axis shows brain regions with significant reduction of cortical thickness, and the y-axis indicates cortical thickness (millimeters). The horizontal thick line inside each box indicates the median value. The upper and lower boundaries of each box mean lower quartile and upper quartile values, respectively. The whiskers represent smallest and largest nonoutlier observations. The circle depicts a mild outlier, and asterisk indicates an extreme outlier. Scatterplots and age correlation slopes for mean cortical thickness (millimeters) with increasing age within regions for UHR and HC subjects. The x-axis indicates age (y), and the y-axis indicates cortical thickness (millimeters). Significant correlations between age and mean cortical thickness within each region are marked (asterisk). UHR, ultra-high-risk (n = 29); schizophrenia (n = 31); HC subjects, healthy control subjects (n = 29); ACC, anterior cingulate cortex.