TABLE 3.

Phenotype and molecular genetics of amc mutants

Strain	CI activity	Fully assembled (950 kDa)	Subcomplex (700 kDa)	Allelism	Monogenic	Tagged
wt	100	++++	—	—	—	—
amc1	12	—	+	No	Yes	No
amc2	4	—	+	No	Yes	No
amc3	41	+++	—	No	Yes	No
amc4	14	+	—	No	Yes	No
amc5	14	—	++	Yes (amc7)	Yes	Yes
amc6	22	—	++	No	Yes	No
amc7	14	—	++	Yes (amc5)	Yes	No

Complex I activity (CI) is indicated as % of wild type (100). +, ++, +++, ++++, and — indicate the relative levels of fully assembled complex I or 700-kDa subcomplexes.