. 2011 Jun;188(2):247–262. doi: 10.1534/genetics.111.127746

TABLE 3.

Reversion rates for deletion and quasipalindrome-associated mutations

		Rate of reversion per 10⁸ cells
Mutation	Strain background	Rate	95th per. (+)	95th per. (−)	N
11-bp deletion	(wt)	6.2	6.6	5.90	34
	mutS	4.9	5.4	4.4	14
	xonA xseA	7.4	8.1	6.8	18
QP3	(wt)	0.16^a	0.26	0.10	12
	mutS	1.3^a	1.4	1.1	19
	xonA xseA	0.51^b	0.64	0.41	17
QP4	(wt)	0.033^c	0.058	0.019	19
	mutS	0.24^c	0.31	0.19	15
	xonA xseA	0.37^b	0.47	0.29	19
QP5	(wt)	9.7^b	11	8.6	10
	mutS	8.3^b	9.8	7.0	13
	xonA xseA	50^b	52	47	15
QP6	(wt)	1.9^b	2.2	1.6	12
	mutS	2.0^b	2.4	1.7	12
	xonA xseA	76^b	80	73	16
−CG	(wt)	0.86	1.08	0.69	12
	mutS	130	130	120	24
	xonA xseA	0.60	0.72	0.50	18

Ninety-fifth percentile (per.) determined by methd described in equations 24 and 25 in Rosche and Foster (2000).

^{^a}

Using the frequency of SacII⁻ revertants (13/15) for the wild-type background and sequence analysis for the mutS background (12/17 templated), the rate of templated mutation at QP3 is calculated to be 1.4 × 10⁻⁹ for wt and 9.2 × 10⁻⁹ for the mutS background.

^{^b}

More than 90% reversions appear to be templated, as determined by sequence analysis and restriction assays.

^{^c}

Using the frequency of SacII⁻ revertants (6/15) for the wild-type background and sequence analysis for the mutS background (4/14 templated), the rate of templated mutation at QP4 is calculated to be 1.3 × 10⁻¹⁰ for wt and 6.9 × 10⁻¹⁰ for the mutS background.