TABLE 1.
Genes showing changes in transcript levels in response to ade2 RNA interference in S2 cells that were also assayed by real-time qRT-PCR
| Gene | Interpro domaina | Log2 fold changeb | P-value |
| ade2 | IPR010073: Phosphoribosylformylglycinamidine synthase | −2.56 | 0.000 |
| RpII215 | IPR000722: RNA polymerase, α-subunit | −2.01 | 0.011 |
| CG17612 | IPR007087: Zinc finger, C2H2-type | −1.09 | 0.025 |
| CG31002 | IPR002213: UDP-glucuronosyl/UDP-glucosyltransferase | 0.88 | 0.044 |
| CG34439 | Unknown | 0.91 | 0.004 |
| 0.93 | 0.007 | ||
| CG13283 | IPR000718: Peptidase M13, neprilysin | 0.94 | 0.004 |
| HtrA2 | IPR009003: Peptidase cysteine/serine, trypsin-like | 1.09 | 0.001 |
| MESK2 | IPR004142: Ndr family (N-myc-downstream-repressed) | 1.10 | 0.009 |
| CG4615 | IPR004254: Hly-III-related (hemolysin III-related) | 1.13 | 0.004 |
| FKBP59 | IPR001179: Peptidyl-prolyl cis-trans isomerase, FKBP-type | 1.35 | 0.001 |
| CG11436 | IPR013026: Tetratricopeptide repeat-containing | 2.05 | 0.000 |
| 2.44 | 0.001 |
a
Interpro domain (Hunter et al. 2009) was reported in FlyBase (Tweedie et al. 2009). In cases where several domains are reported, one functionally descriptive entry was selected.
b
Log2 fold change absolute values ≥0.9 as detected by microarray analysis. Transcripts showing two values correspond to the values for two different oligonucleotides on the microarray. See Table S2 for details.