Table 1.
Isolate and populationa | MIC (μg/ml) |
||
---|---|---|---|
CPTb | DAP6 | DAP10 | |
R5717 | 0.25 | 2 | 2 |
T96 | 0.25 | 8 | 4–8 |
T96 M | NAc | 8 | 8 |
R5563 | 0.5 | 2 | 2 |
T96 | 0.5 | 8 | 4 |
T96 M | NA | 8 | NA |
R5995 (VISA) | 0.5 | 4 | 4 |
T96 | 0.5 | 4 | 4 |
T96 M | NA | 16 | NA |
R5996 (hVISA) | 0.5 | 4 | 4 |
T96 | 0.5 | 8–16 | 4–8 |
T96 M | NA | 8–16 | 16 |
T96, overall bacterial population at 96 h; T96 M, mutant bacterial population at 96 h.
CPT was used at 600 mg q12h.
NA, no resistant mutants recovered.