Table 5.
Relative importance of each risk factor measured during a simulated clinical trial of AS-MQ, determined using Wald and odds ratio statisticsa
| Risk factor | Output |
||
|---|---|---|---|
| Wald statistic | Odds ratio (95% CI) | P value | |
| Log P0 | 0.000 | 0.977 (0.509-1.951) | 0.992 |
| Location (high EIR) | 7.505 | 0.991 (0.985-0.997) | 0.006 |
| Age (under 5 years) | 3.217 | 1.704 (0.952-0.3051) | 0.073 |
| Day 7 serum level (<15th centile) | 10.102 | 2.939 (1.512-5.713) | 0.001 |
| Constant | 0.155 | 0.209 | 0.694 |
a
The overall failure rate was 15.75%, and results came from logistic regression analysis with treatment failure as the outcome.