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Effect of micafungin on the density of Candida albicans SC5313 A15 heterozygous mutant in the kidneys of mice as a function of time. (A) Controls; (B) micafungin at 1 mg/kg administered at 5, 29, and 53 h; (C) micafungin at 5 mg/kg administered at 5, 29, and 53 h; (D) micafungin at 20 mg/kg administered at 5, 29, and 53 h. Data are means ± SDs. The solid line is the fit of the population mathematical model.
