Fig. 5.

Gametocyte densities and mosquito infection rates. Data from two transmission studies of asymptomatic children in Burkina Faso (335) and symptomatic children 2 weeks after antimalarial treatment in Kenya (55, 402) were combined. Both studies determined gametocyte carriage by Pfs25-specific QT-NASBA and offered venous blood to mosquitoes in a membrane feeding assay (see “Evidence for Naturally Acquired Transmission-Blocking Activity”) to determine the proportion of infected mosquitoes. Circles indicate aggregated data, grouped in 10 categories of similar gametocyte densities.