Table 3.
Clinical presentation of dematiaceous molds
Condition | Clinical presentation | Tissues involved | General agents that can cause the entity | Molds most frequently associated with clinical presentation | Other molds associated |
---|---|---|---|---|---|
Eumycetoma | Painless mass in extremities with multiple sinuses that drain pus and grains | Skin, soft tissues, fascia, bone | Bacteria, hyaline and pigmented molds | Madurella spp. | Scedosporium, Acremonium, Exophiala, Aspergillus, and others |
Chromoblastomycosis | Tumor-like lesions of skin (nodules, verruca, scar, plaques) | Skin, underlying soft tissues | Pigmented molds | Fonsecaea pedrosoi, Cladophialophora carrionii | Phialophora verrucosa, Rhinocladiella spp., Exophiala spp., and others |
Phaeohyphomycosis | Immunocompetent individuals present with single lesion (cyst, plaque) in the area of inoculation; in immunosuppressed patients the inoculation site may be a nodule, eschar, ulcer, or other and may disseminate to other organs | Skin, soft tissue, sinuses, lungs, brain | Pigmented molds | Exophiala jeanselmei, Exophiala dermatitidis, Bipolaris spp. | Alternaria, Curvularia, Exserohilum |