Table 1.
Severity of inflammatory cell infiltration into lung tissues after immunization
| Treatment group | Mean infiltration ± SDa |
||
|---|---|---|---|
| Perivascular and peribronchiolar eosinophilia | Edema | Epithelial damage | |
| Control | 0† | 0† | 0† |
| Model | 8.58 ± 0.58* | 8.25 ± 0.67* | 8.16 ± 0.54* |
| pcDNA3.1 | 7.37 ± 0.62* | 7.86 ± 0.59* | 7.63 ± 0.47* |
| OVA-pcDNA3.1 | 3.68 ± 0.37*‡ | 3.96 ± 0.37*‡ | 3.64 ± 0.28*‡ |
| OVA-CTLA-4-pcDNA3.1(L) | 3.49 ± 0.48*‡ | 3.73 ± 0.52*‡ | 3.51 ± 0.34*‡ |
| OVA-CTLA-4-pcDNA3.1(H) | 1.18 ± 0.16† | 1.16 ± 0.19† | 0.97 ± 0.15† |
a
*, P < 0.05 compared to the control and OVA-CTLA-4-pcDNA3.1(H) groups; †, P < 0.01 compared to the model and pcDNA3.1 groups; ‡, P < 0.05 compared to the model and pcDNA3.1 groups.