Fig. 2.

Locations of immunoreactive regions in PCV2 CP. Underlined regions in the PCV2a genotype peptide sequence show the locations of the immunoreactive regions described by Lekcharoensuk et al. (26) using MAbs prepared against whole purified virus (strain ISU 31, GenBank accession number AJ223185). The underlined regions in the PCV2b genotype sequence (GenBank accession number AF201311) summarize the results obtained from the pepscan analysis by Mahé et al. (33). The epitope maps are combined to yield the shaded peptide sequences, identified as epitope regions A, B, C, and D. Amino acids in bold show the location of an immunodominant region described by Truong et al. (55). The box identifies the putative receptor binding region described in the work of Misinzo et al. (36).