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. 2011 Apr;18(4):647–654. doi: 10.1128/CVI.00435-10

Fig. 7.

Fig. 7.

MN vaccination with trimeric sHA induces improved clearance of virus from the lung. Mice primed and boosted with 3 μg of recombinant soluble HA by the microneedle or subcutaneous routes were challenged with 5 LD50 of mouse-adapted A/Aichi/2/68. Lungs were removed on day 4 postchallenge and processed for virus plaque assays. Lung viral titers are reported as the arithmetic mean ± standard deviation (n = 3). ND, not detectable.