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Type 1 polarization by NLGP-matured DCs. Immature DCs generated from monocytes obtained from CaCx patients (n = 6) and healthy individuals (n = 6) were matured in vitro with NLGP/LPS, and the secretory statuses of type 1 cytokine IL-12 (A) and type 2 cytokine IL-10 (B) were assessed in culture supernatants by ELISA. The mean ± SD is presented in each case. *, P < 0.001 (for iDCs versus NLGP/LPS DCs from healthy individuals and for iDCs versus NLGP/LPS DCs from CaCx patients).
