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. 2011 Apr 30;35(2):130–137. doi: 10.4093/dmj.2011.35.2.130

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Copyright © 2011 Korean Diabetes Association

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 3 — Transforming growth factor (TGF)-β and collagen type IV mRNA expression by real time RT-PCR. Compared with the CO and LO groups, TGF-β and collagen type IV mRNA expression of the SPR and COM groups were significantly decreased. CO, control Otsuka-Long-Evans-Tokushima-Fatty (OLETF) group; SPR, spironolactone-treated OLETF group; LO, losartan-treated OLETF group; COM, spironolactone- and losartan-treated OLETF group. ^aP<0.05 compared with CO group, ^bP<0.05 compared with LO group.