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. 2011 Jul;52(7):1411–1419. doi: 10.1194/jlr.P013672

TABLE 3.

Chromosomal Regions with Multipoint LOD score > 2.0 for Lipid Quantitative Traits

Region	Trait^a	Nearest Marker	cM	h²_q	LOD	Empirical P^b	1-LOD Interval, Mb	References^c
7p12	LDL-C/HDL-C	D7S1818	67	0.36	3.91	0.00007	37-60	35–39
15q23-24	TG	D15S131/D15S655	76	0.26	2.33	0.0004	65-91	17, 57–61
16q23	TC	D16S3091	111	0.33	3.35	<0.00007	79-84	36, 40–43
	LDL-C	D16S3091	111	0.26	2.40	0.0009	79-84	36, 40–43
19q12	TC	D19S433	52	0.23	2.12	0.001	12-39	5, 13, 16, 52–56
	LDL-C	D19S433	52	0.26	2.68	0.0005	16-39	5, 13, 16, 52–56
20p12	LDL-C	D20S851	21	0.28	2.16	0.001	00-11	54, 62

h²_q, locus-specific heritability; Mb, megabase.

^a

Traits were log-transformed.

^b

Empirical P was based on 15,000 replicates for the specific trait.

^c

Linkage was reported for lipid traits in previous studies.