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. 2011 May 25;31(21):7670–7681. doi: 10.1523/JNEUROSCI.0629-11.2011

Figure 6.

Figure 6.

Cone-mediated responses in ventral Gnat1−/− retina are resistant to bleaching with green light. A, LN models for a Gnat1−/− OFF ganglion cell at three light levels (mean luminance, 140, 2000, and 12,000 R*/cone/s). B, Fourier transform of the filters in A. The filter in the 12,000 R*/cone/s condition was normalized with a peak of +1 (ON cells) or −1 (OFF cells) before scaling the other two conditions (after aligning the nonlinearities) and computing the Fourier transform. Other conventions are the same as for Figure 5. C, Zero-cross time at three levels of mean luminance across cells. D, Averaged Fourier transform of filters at three levels of mean luminance across cells. E–H, Same as A–D after bleaching with a green light stimulus sufficient to bleach the rod-mediated response in a Gnat2cpfl3 retina (see Results). Blue points in G show the zero-cross times from the control condition in C. There was a slightly delayed zero-cross time at each mean luminance, possibly caused by bleaching of a small percentage of M-opsin expression in the ventral cones.