Table 4.
Open Radical Prostatectomy: Oncologic Outcomes
| |
|
|
Pathologic staging |
Positive surgical margins |
||||
|---|---|---|---|---|---|---|---|---|
| Authors | Year of publication | Patients (N) | pT2 (%) | pT3 (%) | pT4 (%) | pT2 (%) | pT3 (%) | Overall (%) |
| Zincke16 | 1994 | 1143 | 53.2 | 34.7 | - | - | - | 12 |
| Grossfeld18 | 2000 | 1383 | 74.5 | 25.5 (pT3 + pT4) | 26 | 67.3 | 34 | |
| Lepor19 | 2001 | 1000 | 76.6 | 21.6 | 1.5 | - | - | 19.9 |
| Hull20 | 2002 | 1000 | 59.5 | 33.3 | - | - | - | 12.8 |
| Augustin21 | 2003 | 1243 | 67 | 31.3 | 1.4 | - | 21.4 | |
| Ward55 | 2004 | 7268 | 69 | 31 | - | 28 | 58 (+EPE) | 38 |
| Han22 | 2004 | 9035 | 58.2 | 38.3 | - | 7.7 | 26.9 | 14.7 |
| Saranchuk24 | 2005 | 647 | 76.5 | 21.5 | 1.9 | - | - | 13 |
| Bianco25 | 2005 | 1746 | 66 | - | - | - | 12 | |
| Orvieto26 | 2006 | 996 | 69.7 | 30.1 | - | 1.7 | 24.9 | 8.8 |
| Porter56 | 2006 | 752 | 54.6 | 37.6 | - | - | - | 37.6 |
| Sacco27 | 2006 | 985 | 57.1 | - | - | - | - | 13.7 |
| Chun57 | 2006 | 4277 | 64.4 | - | - | - | - | 21.5 |
| Sengupta29 | 2008 | 6496 | 69.1 | 25.7 (pT3 + pT4) | - | - | 38.2 | |
| Schroeck30 | 2008 | 435 | 74.5 | 25.5 (pT3 + pT4) | - | - | 28 | |
| Chan31 | 2008 | 340 | 66.4 | 33.1 | 0.5 | 22.5 | 56.7 | 34 |
| Eastham32 | 2008 | 1577 | 71 | 28 EPE 6 SVI | - | - | - | 11 |
| Touijer33 | 2008 | 818 | - | 32 EPE6 SVI | - | - | - | 11 |
| Krambeck35 | 2009 | 588 | 88.6 | 10.1% (pT3 + pT4) | - | - | 17 | |
| Weighted means | 64.3 | 31.5 | 1.54 | 16.8 | 42 | 24 | ||
EPE = extraprostatic extension; SVI = seminal vesicle invasion.