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. 2011 Jun;18(6):795–807. doi: 10.1089/cmb.2011.0027

FIG. 2.

FIG. 2.

SOLiD colors represent the transition between the nucleotides. This unique encoding scheme results in each nucleotide being sequenced twice, decreasing the probability of sequencing errors being interpreted as SNPs. However, color signals are not independent, making necessary new methods to accurately determine polymorphism.