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. 2011 Jun;18(6):795–807. doi: 10.1089/cmb.2011.0027

FIG. 8.

FIG. 8.

Drosophila simulation: The precision of different algorithms when confronted with adjacent SNPs show the problems with converting the color reads to nucliotide space. Adjacent SNPs generate color signatures which could also be interpreted as color errors by the translation algorithm. Information is lost in the translation, and the SNP calling precision is affected.