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. Author manuscript; available in PMC: 2011 Jun 24.

Published in final edited form as: J Biomed Mater Res A. 2009 Jun;89(3):632–641. doi: 10.1002/jbm.a.32015

Ex vivo 90 day samples were fixed in 10% buffered formalin, decalcified in Richard’s Decal Solution, embedded in paraffin, sectioned and stained for hematoxylin and eosin. Black squares ( ) indicate edges of the scaffold to demonstrate differences in thickness. A: Percent of the defect area covered by tissue following 90 days in vivo. This measurement assumes a correlation between the amount of polymer degraded to allow for tissue integration. *Significant compared with hollow 500 μm, where p < 0.05. **Significant compared with hollow 500 μm, where p < 0.1. [Color figure can be viewed in the online issue, which is available at www.interscience.wiley.com.]

Inline graphic — Ex vivo 90 day samples were fixed in 10% buffered formalin, decalcified in Richard’s Decal Solution, embedded in paraffin, sectioned and stained for hematoxylin and eosin. Black squares ( ) indicate edges of the scaffold to demonstrate differences in thickness. A: Percent of the defect area covered by tissue following 90 days in vivo. This measurement assumes a correlation between the amount of polymer degraded to allow for tissue integration. *Significant compared with hollow 500 μm, where p < 0.05. **Significant compared with hollow 500 μm, where p < 0.1. [Color figure can be viewed in the online issue, which is available at www.interscience.wiley.com.]