Table 2.

Results of Z and/or S allele carriage determining α₁AT deficiency (under a codominant model) and association with WG^*

Genotype	Cases, no. (%)	Controls, no. (%)	OR (95% CI)	P
All genotypes
MM	353 (81.5)	371 (88.1)	1 (reference)	–
MS and MZ	70 (16.2)	50 (11.9)	1.47 (0.98–2.22)	0.06
SS, ZZ, and SZ	10 (2.3)	0 (0)	14.58 (2.33–∞)	0.002
S genotypes excluded
MM	353 (92.2)	371 (95.4)	1 (reference)	–
MZ	26 (6.8)	18 (4.6)	1.52 (0.79–2.99)	0.24
ZZ	4 (1.0)	0 (0)	5.53 (0.69–∞)	0.11
Z genotypes excluded
MM	353 (88.0)	371 (92.1)	1 (reference)	–
MS	44 (11.0)	32 (7.9)	1.44 (0.87–2.41)	0.16
SS	4 (1.0)	0 (0)	5.53 (0.69–∞)	0.11

^*OR = odds ratio; 95% CI = 95% confidence interval (see Table 1 for other definitions).