FIGURE 1.

A, relative abundance of the two major classes of mycolic acids, α and keto, present in M. leprae bacteria. B, chain length distribution of these M. leprae mycolic acids. C, LC/MS-MS analysis showing that the C-22 α chain is predominant in the mycolic acids of M. leprae (spectrum shown is from the α-78 where m/z 1136 was targeted). D, relative abundance of the three major classes of mycolic acids, α, methoxy, and keto, present in M. tuberculosis bacteria. E, chain length distribution of these M. tuberculosis mycolic acids. F, LC/MS-MS analysis showing that the C-26 α chain is predominant in the mycolic acids of M. tuberculosis (spectrum shown is from the α-78 where m/z 1136 was targeted). Four separate samples were analyzed, and the values presented here are the average of those; the standard deviation is shown on the graphs.