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The kinetics of the Ci-VSP cytoplasmic region toward PtdIns(3,4,5)P3 and PtdIns(4,5)P2. The initial rate of WT and Glu-411 mutants of Ci-VSP cytoplasmic region-catalyzed dephosphorylation of PtdIns(3,4,5)P3 (A) and PtdIns(4,5)P2 (B) was determined using various concentrations of PtdIns(3,4,5)P3 and PtdIns(4,5)P2. n = 5.
