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. 2011 May 5;286(26):23378–23387. doi: 10.1074/jbc.M111.236372

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FIGURE 6. — Differential mobility of IP₃R2 in different subcellular regions. Typical FRAP experiments are shown for EGFP-IP₃R2 (A) and EGFP-IP₃R3 (B), with ROI (white circles) chosen to capture IP₃R within the perinuclear (upper panels) or peripheral (lower panels) regions of the cell. Images are shown after recovery periods of at least 300 s. Scale bars = 10 μm. The results are typical of recordings from 10–15 cells from three independent transfections. Summary results (means ± S.E., n = 10–15) are shown for M_f (C and D) and D (E and F) determined for each IP₃R subtype in the cell periphery (open bars) or perinuclear region (closed bars).