TABLE 5.

Rates of reduction (s⁻¹) by l-Cys of metHb in solution and sol-gel (s⁻¹)

Sample	Solutiona	T stateb	R stateb	Metb
HbE	2.30 × 10−3 ± 0.4	6.3 × 10−5 ± 0.4	1.9 × 10−4 ± 0.1	6.2 × 10−5 ± 0.4
		3.9 × 10−3 ± 0.2
HbA	2.10 × 10−4 ± 0.01	4.2 × 10−5 ± 0.6	1.3 × 10−4 ± 0.1	3.6 × 10−5 ± 0.6
		3.0 × 10−3 ± 0.4
Mb (horse)	1.51 × 10−5 ± 0.01

^a Solution phase is 0.38 mm (heme) + 2 mm l-Cys, PBS, pH 7.4. Data were analyzed by monitoring the change in the met absorbance band at 630 nm over time. n = 3 for HbE and n = 2 for HbA.

^b Sol-gel is 0.45 mm (heme) + 10 mm l-Cys, PBS, pH 7.4. Sol-gel data were analyzed as described for solution.