Table 5.
Medical Diagnosis | Overall | Control | Clinical Seizures | Subclinical Seizures | |
---|---|---|---|---|---|
Prematurity | 15% | 13% | 15% ns | 16% ns,ns | |
Cerebral Palsy | 4% | 1% | 5% ns | 3% ns,ns | |
Sensory Integration Disorder | 51% | 53% | 48% ns | 58% ns,ns | |
ADHD | 31% | 31% | 30% ns | 31% ns,ns | |
Hypotonia | 24% | 20% | 26% ns | 27% ns,ns | |
Mental Retardation | 20% | 7% | 28% † | 18% ns,ns | |
Mitochondrial disorder | 10% | 6% | 11% ns | 17% ns,ns | |
Genetic Disorder | 6% | 4% | 7% ns | 7% ns,ns | |
Renal disease | 2% | 2% | 2% ns | 1% ns,ns | |
Cardiovascular disease | 2% | 2% | 2% ns | 2% ns,ns | |
Hematological disease | 1% | 1% | 1% ns | 1% ns,ns | |
Growth | |||||
Failure-to-Thrive | 14% | 11% | 14% ns | 15% ns,ns | |
Macrocephaly | 11% | 9% | 11% ns | 13% ns,ns | |
Accelerated Growth | 10% | 11% | 9% ns | 9% ns,ns | |
Microcephaly | 4% | 4% | 4% ns | 3% ns,ns | |
Gastrointestinal Disorders | |||||
Constipation | 41% | 39% | 42% ns | 40% ns,ns | |
GERD | 22% | 22% | 22% ns | 25% ns,ns | |
Inflammation | 17% | 12% | 18% ns | 24% ns,ns | |
Dysbiosis | 16% | 12% | 16% ns | 22% ns,ns | |
LNH | 4% | 2% | 4% ns | 7% ns,ns | |
Sleep Disorders | |||||
Disrupted Sleep | 44% | 34% | 47% ns | 53% ns,ns | |
Insomnia | 22% | 27% | 34% ns | 33% ns,ns | |
Apnea | 9% | 8% | 9% ns | 9% ns,ns | |
PLMS | 6% | 5% | 6% ns | 9% ns,ns |
†p < = 0.0001
For each characteristic listed, statistical comparisons were made between the clinical seizure group and the control group (superscript after the clinical seizure percentage), the subclinical seizure group and the control group (1st superscript after the subclinical seizure percentage) and between the clinical and subclinical seizure group (2nd superscript after the subclinical seizure percentage). There are 24 medical diagnoses and 3 comparisons for each medical diagnosis resulting in 72 comparisons. The Bonferroni correction results in an alpha of 0.05/72 = 0.0007, so we have set the alpha to p < = 0.0001 to be conservative.