Table 1.

Effects of hydroalcoholic extract of A. caudatus on Selective biochemical parameters in rabbits fed with high cholesterol diets on 0, 45^th and 75^th days

Biochemical parameters	Duration (days)	GroupI	GroupΙΙ	GroupIII	GroupIV	GroupV
	0	41.4 ± 8.443933	47.6 ± 7.436397	46.8 ± 7.463243	45.4 ± 8.792042	45.8 ± 6.723095
	45	46.8 ± 7.463243	898.2 ± 84.3872	664 ± 192.3382	786.2 ± 180.7836	876.8 ± 100.3927
Cholesterol(m g/dl)	75	47.6 ± 7.436397	-------------	1053.2 ± 34.76636	1020.8 ± 72.58237	575 ± 34.12477ba
	0	45.267 ± 11.58879	55.8 ± 6.797058	58.2 ± 7.823043	44.2 ± 12.39758	59 ± 10.65364
	45	45.267 ± 12.39758	166.2 ± 30.32656	109.4 ± 20.59854	156.2 ± 36.46505	131.6 ± 7.700649
Triglyceride (mg/dl)	75	46.233 ± 1.16301	-------------	238.4 ± 55.13892	195.8 ± 54.29273	85.6 ± 7.700649
	0	16.42 ± 1.99925	17.42 ± 1.485598	15.086 ± 1.117578	16.96 ± 1.7358	16.98 ± 1.01341
	45	17.1 ± 1.604681	837.2 ± 65.78146	839.2 ± 46.21904	813.2 ± 73.41117	660.62 ± 361.4526
LDL-cholesterol mg/dl)	75	17.38 ± 1.070981	--------------	952.98 ± 50.06078	694.88 ± 45.25231b	426.8 ± 36.0236b
	0	23.4 ± 9.607289	16.8 ± 3.114482	18.6 ± 2.607681	17.4 ± 3.130495	19.4 ± 6.107373
	45	20.8 ± 5.630275	61.6 ± 12.05404	56.8 ± 10.56882	82 ± 14.91643	70.8 ± 10.84896
HDL- cholesterol (mg/dl)	75	19 ± 5.43139	--------------	81.2 ± 16.42255	86.4 ± 17.85497	134.2 ± 11.14451ba
	0	8.2 ± 1.48324	10.2 ± 4.91935	13.6 ± 4.037326	14.2 ± 3.563706	14.4 ± 3.781534
	45	14 ± 4.52769	34.8 ± 10.32957	30 ± 9.082951	27 ± 5.522681	28.8 ± 4.658326
apolipoprotein B (mg/dl)	75	9.8667 ± 1.30384	-------------	58.2 ± 11.43241	49.2 ± 11.64903	41 ± 8.602325
	0	43 ± 9.823441	42.2 ± 9.364828	43.6 ± 11.90798	41.8 ± 8.757854	41.4 ± 12.83745
	45	47.8 ± 5.215362	27.2 ± 7.362065	27.6 ± 7.924645	28.8 ± 6.648308	29.6 ± 6.308724
apolipoprotein A (mg/dl)	75	34.8 ± 8.288546	--------------	22.4 ± 7.765307	21 ± 9.66954	52.4 ± 8.961027ba
	0	0.3 ± 0.141421	0.16 ± 0.089443	0.2 ± 0.141421	0.2 ± 0.141421	0.2 ± 0.1
	45	0.2 ± 1.604681	0.7 ± 0.070711	0.68 ± 0.164317	0.64 ± 0.151658	0.7 ± 0.070711
de Malondialdehy (mol/l)	75	0.22 ± 0.130384	--------------	1.7 ± 0.234521	0.92 ± 0.204939b	0.35 ± 0.070711ba
	0	3.02 ± 0.141421	3.66 ± 1.934683	2.26 ± 1.062073	2.66 ± 1.825651	2.32 ± 1.634625
C-reactive protein (mg/l)	45	2.96 ± 1.564609	12.82 ± 3.094673	11.36 ± 3.706481	14.08 ± 2.259867	12.46 ± 3.304996
	75	2.58 ± 1.88202	--------------	23.4 ± 3.361547	8.9 ± 0.514782b	5.1 ± 1.031988ba
	0	15.12 ± 1.41492	15.26 ± 1.209545	15.22 ± 1.243785	15.72 ± 2.667771	14.46 ± 1.209545
	45	16.22 ± 2.615722	23.32 ± 2.963444	23.32 ± 3.013636	25.72 ± 4.130617	26.12 ± 3.62519
OX- LDL(ng/ml)	75	15.5 ± 2.382226	--------------	35.12 ± 5.157713	25.54 ± 3.72599	18.82 ± 1.411382b
	0	42.358 ± 8.124376	46.554 ± 7.265138	45.284 ± 8.458223	45.862 ± 12.62378	44.846 ± 6.728988
	45	45.926 ± 7.531051	884.204 ± 83.63083	729.088 ± 148.0296	738.548 ± 148.253	867.5016 ± 102.6377
AI	75	46.642 ± 7.538247	--------------	1040.96 ± 33.85897	1011.03 ± 26.33166	551.062 ± 71.06503b

Group І: Fed with Normal diet (control group) (75^th days)

Group ΙΙ: Normal diet + cholesterol (45^th days)

Group ΙIΙ: Normal diet + cholesterol (75^th days)

Group ΙV: Normal diet + cholesterol for 45^th days and Normal diet for 30^th days

Group V: Normal diet + cholesterol for 45^th days and Normal diet + A. caudatus for 30^th days

b Significant difference between Group III with Groups IV Group V. (p < 0.05)

c Significant difference between Group IV with Group V. (p < 0.05)

Cho: total cholesterol, TG:Triglyceride, LDL-C: LDL-cholesterol, HDL-C: HDL-cholesterol, ApoB:apolipoproteinB, ApoA:polipoproteinA, MDA: malondialdehyde,

CRP:C-reactive protein, AI: atherosclerosis index