Table 1.
Differentially expressed glycolytic and related proteins in Hepa-1 c4 and WT tumours.
| Spot number | Protein Name | c4/WT Ratio | P values |
|---|---|---|---|
| 47 | Triose-phosphate isomerase (EC 5.3.1.1). | -1.46 | 0.0005 |
| 42 | Glyceraldehyde-3-phosphatedehydrogenase | -1.35 | 0.0530 |
| (EC1.2.1.12). | |||
| 52 | Phosphoglycerate kinase (EC 2.7.2.3). | -1.89 | 0.0005 |
| 41 | Phosphoglycerate mutase (EC 5.4.2.1). | -1.44 | 0.0005 |
| 49 | Fructose bisphosphate Aldolase A (EC 4.1.2.13). | -2.05 | 0.0005 |
| 57 | Enolase (EC 4.2.1.11). | -1.35 | 0.0005 |
| 60 | Pyruvate kinase (EC 2.7.1.40). | -1.69 | 0.0005 |
| 59 | D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95). | -2.39 | 0.0005 |
| 73 | L-Lactate dehydrogenase A (EC 1.1.1.27). | -1.25 | 0.0140 |
Differences in 2D gels between the Hepa-1 c4 and WT tumours.
The c4/WT ratios of proteins are selected as differences in 2D gels between the Hepa-1 c4 (n = 3) and WT (n = 3) tumours, each one with a technical replicate using reciprocal labeling. The software produces 'fold' differences and P-values (t-test). The negative ratios indicate less in the Hepa-1 c4 than WT. See Additional File for list (Table S1) of all the protein changes.