Skip to main content

View full-text article in PMC

. 2011 Jun 24;6(6):e21447. doi: 10.1371/journal.pone.0021447

Table 2. Minimally adjusted association between initiation of an antidepressant agent (exposed versus unexposed) and hospitalization for gastrointestinal bleeding in warfarin users.

Variables	0 to 29 days			30 to 59 days			60 to 119 days
	(1^st prescription)^*			(2^nd prescription)^*			(3^rd or 4^th prescription)^*
	OR	Lower	Upper	OR	Lower	Upper	OR	Lower	Upper
		95% CI	95% CI		95% CI	95% CI		95% CI	95% CI
Citalopram	2.28	1.66	3.13	1.31	0.80	2.16	1.58	1.07	2.34
Escitalopram	1.58	1.10	2.27	1.31	0.82	2.10	1.27	0.86	1.88
Fluoxetine	1.94	1.34	2.83	1.06	0.55	2.06	0.84	0.45	1.56
Paroxetine	1.94	1.51	2.49	1.49	1.03	2.14	1.30	0.93	1.81
Sertraline	1.51	1.15	1.98	1.49	1.05	2.11	1.48	1.10	1.98
Venlafaxine	1.82	1.13	2.93	0.77	0.32	1.86	1.80	1.09	2.97
Amitriptyline	1.66	1.16	2.39	0.98	0.51	1.90	1.84	1.18	2.88
Nortriptyline	1.66	0.78	3.54	No data^†			No data^†
Mirtazapine	2.49	1.86	3.33	0.92	0.52	1.63	1.34	0.90	2.00

*Adjusted for age, gender, race, and number of prior warfarin prescriptions filled on the index date.

^†

Insufficient number of exposed cases or controls to analyze.