Distribution of amount of within-woman change in circulating DHEAS in the 20 women with BSO surgery at the pre-or early perimenopausal stage who were followed for at least one year post-surgery (n=20). Six of these women (30%) exhibited declines in DHEAS while 14 (70%) had a rise in DHEAS. Estimated within-woman changes were adjusted for age, ethnicity, clinical site, smoking, height and weight, and prior HT use.