Table 2.
Symptoms of gastroparesis
| CUNV with normal gastric emptying† (N = 106) | Gastroparesis with delayed emptying* (N = 319) | P§ | |
|---|---|---|---|
| Nausea, N (%) | 0.85 | ||
| None | 5 (4.7) | 15 (4.7) | |
| Very mild | 5 (4.7) | 26 (8.2) | |
| Mild | 11 (10.4) | 35 (11.0) | |
| Moderate | 26 (24.5) | 78 (24.5) | |
| Severe | 27 (25.5) | 85 (26.7) | |
| Very severe | 32 (30.2) | 80 (25.1) | |
| Retching, N (%) | 0.66 | ||
| None | 37 (34.9) | 102 (32.0) | |
| Very mild | 13 (12.3) | 37 (11.6) | |
| Mild | 18 (17.0) | 40 (12.5) | |
| Moderate | 14 (13.2) | 62 (19.4) | |
| Severe | 15 (14.2) | 49 (15.4) | |
| Very severe | 9 (8.5) | 29 (9.1) | |
| Vomiting, N (%) | 0.23 | ||
| None | 44 (41.5) | 106 (33.2) | |
| Very mild | 9 (8.5) | 31 (9.7) | |
| Mild | 11 (10.4) | 29 (9.1) | |
| Moderate | 10 (9.4) | 61 (19.1) | |
| Severe | 17(16.0) | 44 (13.8) | |
| Very severe | 15 (14.2) | 48 (15.1) | |
| Stomach fullness, N (%) | 0.71 | ||
| None | 2 (1.9) | 10 (3.2) | |
| Very mild | 4 (3.8) | 18 (5.7) | |
| Mild | 7 (6.6) | 31 (9.8) | |
| Moderate | 34 (32.1) | 83 (26.2) | |
| Severe | 32 (30.2) | 86 (27.1) | |
| Very severe | 27 (25.5) | 89 (28.1) | |
| Unable to finish meal, N (%) | 0.56 | ||
| None | 7 (6.6) | 20 (6.3) | |
| Very mild | 3 (2.8) | 19 (6.0) | |
| Mild | 12 (11.3) | 38 (11.9) | |
| Moderate | 24 (22.6) | 77 (24.1) | |
| Severe | 24 (22.6) | 84 (26.3) | |
| Very severe | 36 (34.0) | 81 (25.4) | |
| Feeling excessively full after meals, N (%) | 0.28 | ||
| None | 4 (3.8) | 12 (3.8) | |
| Very mild | 2 (1.9) | 20 (6.3) | |
| Mild | 6 (5.7) | 34 (10.7) | |
| Moderate | 25 (23.6) | 74 (23.2) | |
| Severe | 31 (29.3) | 80 (25.1) | |
| Very severe | 38 (35.9) | 99 (31.0) | |
| Loss of appetite, N (%) | 0.90 | ||
| None | 8 (7.6) | 32 (10.0) | |
| Very mild | 9 (8.5) | 22 (6.9) | |
| Mild | 20 (18.9) | 70 (21.9) | |
| Moderate | 23 (21.7) | 67 (21.0) | |
| Severe | 22 (20.8) | 66 (20.7) | |
| Very severe | 24 (22.6) | 62 (19.4) | |
| Bloating, N (%) | 0.07 | ||
| None | 10 (9.4) | 28 (8.8) | |
| Very mild | 2 (1.9) | 31 (9.7) | |
| Mild | 13 (12.3) | 44 (13.8) | |
| Moderate | 29 (27.4) | 60 (18.8) | |
| Severe | 26 (24.5) | 79 (24.8) | |
| Very severe | 26 (24.5) | 77 (24.1) | |
| Stomach visibly larger, N (%) | 0.84 | ||
| None | 23 (21.7) | 64 (20.1) | |
| Very mild | 10 (9.4) | 21 (6.6) | |
| Mild | 14 (13.2) | 38 (11.9) | |
| Moderate | 19 (17.9) | 63 (19.8) | |
| Severe | 15 (14.2) | 58 (18.2) | |
| Very severe | 25 (23.6) | 75 (23.5) | |
| Gastroparesis cardinal symptom index (GCSI), median (IQR) | 3.2 (2.3, 3.7) | 3.1 (2.2, 3.7) | 0.84 |
Symptoms shown were collected from the Patient Assessment of Upper Gastrointestinal Disorders Symptom Severity Index (PAGI-SYM). Severity as assessed for period covering the past two weeks.
†
Gastroparesis; based on delayed gastric emptying scintigraphy >60% retention at 2 hours or >10% retention at 4 hours.
‡†
Chronic Unexplained Nausea and Vomiting
§
P values based on Fishers exact test.
¶
P values based on Cochran-Armitage test for trend.