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Caspase-1 inhibitor, Ac-YVAD-CHO inhibited the Substance P (SP) (10−8 M), not calcitonin-gene related peptide (CGRP) (10−8 M), induced interleukin (IL)-1β protein production (A and B) in the REK cultures. Values are means ± SE. ** p<0.01 vs. the control cells. # p<0.05 vs. the cultures treated with SP or CGRP.
