TABLE 5.

Shown are all hematopoietic stem cell (HSC) and protein kinase gene sets that were significantly enriched (p < 0.05, false discovery rate {FDR} < 0.25) in the high-frequency (HF) versus low-frequency (LF) curated gene set enrichment analysis

Gene set	P value	FDR	Up in HF or LF
STEMCELL_COMMON_UP	<0.001	<0.001	HF
HSC_EARLYPROGENITORS_SHARED	0.0020	0.0037	HF
HSC_EARLYPROGENITORS_FETAL	<0.001	0.0049	HF
HSC_EARLYPROGENITORS_ADULT	<0.001	0.0051	HF
HSC_LATEPROGENITORS_SHARED	<0.001	0.0087	HF
HSC_MATURE_ADULT	<0.001	0.0098	HF
HSC_MATURE_FETAL	<0.001	0.016	HF
HADDAD_HSC_CD7_UP	0.0021	0.018	HF
HSC_LATEPROGENITORS_ADULT	0.0041	0.018	HF
HSC_HSCANDPROGENITORS_SHARED	0.0098	0.040	HF
HSC_HSCANDPROGENITORS_FETAL	0.0064	0.044	HF
HSC_MATURE_SHARED	0.0080	0.046	HF
HSC_HSCANDPROGENITORS_ADULT	0.0058	0.050	HF
BYSTRYKH_HSC_BRAIN_TRANS_GLOCUS	0.0060	0.13	LF
BYSTRYKH_HSC_CIS_GLOCUS	0.049	0.23	LF
PKC	<0.001	<0.001	HF
PKA	0.002	0.002	LF

There are far more HSC gene sets associated with the HF end of the basilar papilla. The PKC and PKA gene sets shown here are as described in Methods