TABLE 3.

Comparison of Younger and Older Patients with a Non-Acetaminophen Etiology (n = 602)

	>60 Years (n = 517)	≥60 Years (n = 85)	P
Females	324 (62.7%)	54 (63.5%)	NS
Symptom duration (days)	12 (0–186)	13 (0–117)	NS
HE coma grade III/IV	341 (66.9%)	56 (65.9%)	NS
INR (AU)	2.6 (1.5–26.1)	2.5 (1.5–18)	NS
ALT (U/L)	839 (3–13,100)	758 (23–10,956)	NS
Bilirubin (mg/dL)	19.3 (0.7–63.3)	14.7 (0.8–43.5)	NS
Creatinine (mg/dL)	1.4 (0.1–74.8)	2.0 (0.3–8.8)	NS
Listed for Tx	300 (58%)	38 (44.7%)	0.03
Contraindications for Tx	95 (18.4%)	25 (29.4%)	0.03
Liver Tx	211 (40.8%)	25 (29.4%)	0.058
Survival after Tx	192 (91.0%)	20 (80.0%)	NS
Spontaneous survival	159 (30.8%)	21 (24.7%)	NS
Overall survival	351 (67.9%)	41 (48.2%)	<0.001

NOTE: Biochemistry values were recorded on admission to study. Values are given as numbers (%) or medians (range).

Abbreviations: ALT, alanine aminotransferase; HE, hepatic encephalopathy; INR, international normalized ratio; NS, not significant; Tx, transplantation.