FIG. 5.

Animals treated at 1-week pi generate polyfunctional CD4 and CD8 responses. (a) SIV-env and gag + pol-specific CD4 and CD8 T cell responses in mesenteric LN collected from untreated (UT; n = 2), short-term treated controller (ST; n = 2), and late-continuous treated (LT; n = 2) animals. (b) Total SIV-env and gag + pol specific CD4 and CD8 T cell responses in mesenteric LN from two UT, ST, and LT animals. All the three SIV-specific cytokines responses against SIV-env, and gag + pol shown in (a) for each animal were added to derive the total response. (c) ADCC titers in plasma of UT, ST, LT, animals at time 0 and week 28 postinfection. Note that only background subtracted data are shown.